Nanohybrids of silver nanoparticles grown in-situ on a graphene oxide silver ion salt: simple synthesis and their enhanced antibacterial activity
-
摘要: 可防治感染性疾病的先进抗菌材料一直是社会的重大需求。目前，各式各样含银纳米抗菌材料已被合成出来，并被认为可应用于许多商业产品领域中。然而，整合与创新基于纳米银的微/纳米结构，对于制备得到性能优异的抗菌剂仍颇具挑战性。基于此，利用简易的超声混合方法，成功合成了一类纳米银颗粒原位生长于氧化石墨烯银盐的纳米复合材料。通过扫描电子显微镜、透射电子显微镜、傅里叶变换红外光谱仪、热重分析仪、X-射线衍射分析仪和X-射线光电子能谱仪等现代分析手段对所得材料纳米结构进行了研究。结果表明，氧化石墨烯不仅可作为带负电荷的大分子捕获大量带正电的银离子，还可作为还原剂将银离子原位还原成纳米银粒子，由此得到了在氧化石墨烯表面同时含有均匀分散的纳米银粒子和银离子的杂化结构。这一先进结构使得所制备的纳米复合材料可充分利用银纳米粒子及氧化石墨烯银盐二者的优势，对金葡菌和大肠杆菌表现出强的抗菌活性和持久的抗菌能力，是一种高效的抗菌剂。Abstract: Advanced antimicrobial agents that treat infectious diseases are greatly needed. Various silver-based nanomaterials have been developed and are considered potential candidates for many commercial products, but they lack durability and adequate antibacterial activity. A new class of nanohybrids of silver nanoparticles (AgNPs) grown in-situ on graphene oxide (GO) using a silver ion salt was synthesized by a simple ultrasonic mixing method. The structure and composition of the nanohybrids were investigated by SEM, TEM, FTIR, TGA, XRD and XPS. Results indicated that GO acts not only as a negatively charged macromolecule for capturing Ag+ ions, but also a reducing agent to reduce the Ag+ ions to AgNPs. The heterogeneous structure leads to abundant well-dispersed AgNPs and Ag+ ions on the GO support. The as-prepared nanohybrids make full use of the advantages of both AgNPs and GO-Ag+ salts, leading to improved and long-term antibacterial activity against both S.aureus and E. coli.
-
Shannon M A, Bohn P W, Elimelech M, et al. Science and technology for water purification in the coming decades[J]. Nature, 2008, 452(7185): 301-310. Fukushima K, Liu S Q, Wu H, et al. Supramolecular high-aspect ratio assemblies with strong antifungal activity[J]. Nature Communications, 2013, 4:2861. Rai M, Yadav A, Gade A. Silver nanoparticles as a new generation of antimicrobials[J]. Biotechnology Advances, 2009, 27(1): 76-83. Panacek A, Kvitek L, Prucek R, et al. Silver colloid nanoparticles: Synthesis, characterization, and their antibacterial activity[J]. The Journal of Physical Chemistry B, 2006, 110(33): 16248-16253. Zou L M, Huang Z H, Kang, F Y, et al. The study of silver-supported phenolic resin-based spherical activated carbon[J]. New Carbon Materials, 2003, 18(3): 214-218. Chen S X, Liu J R, Zeng H M. Comparison of the antibacterial activity of several kinds of activated silver-supporting carbon fibers[J]. New Carbon Materials, 2002, 17(1): 26-29. Feng Q L, Wu J, Chen G Q, et al. A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus[J]. Journal of Biomedical Materials Research, 2000, 52(4): 662-668. Morones J R, Elechiguerra J L, Camacho A, et al. The bactericidal effect of silver nanoparticles[J]. Nanotechnology, 2005, 16(10): 2346-2353. Sondi I, Salopek-Sondi B. Silver nanoparticles as antimicrobial agent: A case study on E-coli as a model for Gram-negative bacteria[J]. Journal of Colloid and Interface Science, 2004, 275(1): 177-182. Li Q L, Mahendra S, Lyon D Y, et al. Antimicrobial nanomaterials for water disinfection and microbial control: Potential applications and implications[J]. Water Research, 2008, 42(18): 4591-4602. Sharma V K, Yngard R A, Lin Y. Silver nanoparticles: Green synthesis and their antimicrobial activities[J]. Advances in Colloid and Interface Science, 2009, 145(1-2): 83-96. Li X, Lenhart J J. Aggregation and dissolution of silver nanoparticles in natural surface water[J]. Environmental Science & Technology, 2012, 46(10): 5378-5386. Sambhy V, MacBride M M, Peterson B R, et al. Silver bromide nanoparticle/polymer composites: Dual action tunable antimicrobial materials[J]. Journal of the American Chemistry Society, 2006, 128(30): 9798-9808. Ray S, Mohan R, Singh J K, et al. Anticancer and antimicrobial metallopharmaceutical agents based on palladium, gold, and silver N-heterocyclic carbene complexes[J]. Journal of the American Chemistry Society, 2007, 129(48): 15042-15053. Zhao L Z, Wang H R, Huo K F, et al. Antibacterial nano-structured titania coating incorporated with silver nanoparticles[J]. Biomaterials, 2011, 32(24): 5706-5716. Jeon H J, Yi S C, Oh S G. Preparation and antibacterial effects of Ag-SiO2 thin films by sol-gel method[J]. Biomaterials, 2003, 24(27): 4921-4928. Ocwieja M, Adamczyk Z. Controlled release of silver nanoparticles from monolayers deposited on PAH covered mica[J]. Langmuir, 2013, 29(11): 3546-3555. Zhang S, Fu R, Wu D, et al. Preparation and characterization of antibacterial silver-dispersed activated carbon aerogels[J]. Carbon, 2004, 42(15): 3209-3216. Zhang S, Fu R, Wu D, et al. Adsorption and antibacterial activity of silver-dispersed carbon aerogels[J]. Journal of Applied Polymer Science, 2006, 102(2): 1030-1037. Fei X, Jia M H, Du X, et al. Green synthesis of silk fibroin-silver nanoparticle composites with effective antibacterial and biofilm-disrupting properties[J]. Biomacromolecules, 2013, 14(12): 4483-4488. Xu W P, Zhang L C, Li J P, et al. Facile synthesis of silver@graphene oxide nanocomposites and their enhanced antibacterial properties[J]. Journal of Materials Chemistry, 2011, 21(12): 4593. Shen J, Shi M, LiN, et al. Facile synthesis and application of Ag-chemically converted graphene nanocomposite[J]. Nano Research, 2010, 3(5): 339-349. Ma J Z, Zhang J T, Xiong Z G, et al. Preparation, characterization and antibacterial properties of silver-modified graphene oxide[J]. Journal of Materials Chemistry, 2011, 21(10): 3350-3352. Ruiz O N, Fernando K A S, Wang B J, et al. Graphene oxide: A nonspecific enhancer of cellular growth[J]. ACS Nano, 2011, 5(10): 8100-8107. Nguyen V H, Kim B K, Jo Y L, et al. Preparation and antibacterial activity of silver nanoparticles-decorated graphene composites[J]. Journal of Supercritical Fluids, 2012, 72: 28-35. Shen J F, Li T, Shi M, et al. Polyelectrolyte-assisted one-step hydrothermal synthesis of Ag-reduced graphene oxide composite and its antibacterial properties[J]. Materials Science and Engineering C, 2012, 32(7): 2042-2047. Jiang B J, Tian C G, Song G, et al. A novel Ag/graphene composite: Facile fabrication and enhanced antibacterial properties[J]. Journal of Materials Science, 2012, 48(5): 1980-1985. Tang J, Chen Q, Xu L G, et al. Graphene oxide-silver nanocomposite as a highly effective antibacterial agent with species-specific mechanisms[J]. ACS Applied Materials & Interfaces, 2013, 5(9): 3867-3874. Wang X D, Zhou N L, Wang W Y, et al. The antimicrobial properties of carboxylated graphene oxide decorated with La particles[J]. New Carbon Materials, 2012, 27(5): 385-392. Hummers W S, Offeman R E. Preparation of graphitic oxide[J]. Journal of the American Chemistry Society, 1957, 80(6): 1339. Krishnamoorthy K, Veerapandian M, Zhang L H, et al. Antibacterial efficiency of graphene nanosheets against pathogenic bacteria via lipid peroxidation[J]. Journal of Physical Chemistry C, 2012, 116(32): 17280-17287. Song J, Kim H, Jang Y, et al. Enhanced antibacterial activity of silver/polyrhodanine-composite-decorated silica nanoparticles[J]. ACS Applied Materials & Interfaces, 2013, 5(22): 11563-11568. Chook S W, Chia C H, Zakaria S, et al. Antibacterial performance of Ag nanoparticles and AgGO nanocomposites prepared via rapid microwave-assisted synthesis method[J]. Nanoscale Research Letters, 2012, 7(1):541. Cui J H, Hu C F, Yang Y H, et al. Facile fabrication of carbonaceous nanospheres loaded with silver nanoparticles as antibacterial materials[J]. Journal of Materials Chemistry, 2012, 22(16): 8121-8126. Li C Y, Wan Y Z, Wang J, et al. Antibacterial pitch-based activated carbon fiber supporting silver[J]. Carbon, 1998, 36(1-2): 61-65. -
下载:
点击查看大图
图(1)
计量
- 文章访问数: 344
- HTML全文浏览量: 188
- PDF下载量: 203
- 被引次数: 0
