Preparation and antibacterial activities of copper nanoparticles encapsulated by carbon

CHEN Hai-feng; WU Juan-juan; WU Ming-yue; JIA Hui

doi:10.1016/S1872-5805(19)60020-X

Volume 34 Issue 4

Turn off MathJax

Article Contents

Article Navigation > New Carbon Mater. > 2019 > 34(4): 382-389

CHEN Hai-feng, WU Juan-juan, WU Ming-yue, JIA Hui. Preparation and antibacterial activities of copper nanoparticles encapsulated by carbon. New Carbon Mater., 2019, 34(4): 382-389. doi: 10.1016/S1872-5805(19)60020-X

Citation:

CHEN Hai-feng, WU Juan-juan, WU Ming-yue, JIA Hui. Preparation and antibacterial activities of copper nanoparticles encapsulated by carbon. New Carbon Mater., 2019, 34(4): 382-389. doi: 10.1016/S1872-5805(19)60020-X

Citation:

PDF( 4242 KB)

Preparation and antibacterial activities of copper nanoparticles encapsulated by carbon

doi: 10.1016/S1872-5805(19)60020-X

1.
Medical School, Nantong University, Nantong 226001, China;
2.
Department of Chemical and Biological Engineering, Nantong Vocational University, Nantong 226007, China

Funds: Jiangsu Students' Platform for Innovation and Entrepreneurship Training Program (201710304157);Science and Technology Project of Nantong (MS12017019-1).

Received Date: 2019-05-10
Accepted Date: 2019-09-10
Rev Recd Date: 2019-07-02
Publish Date: 2019-08-28

Abstract

Abstract

Copper nanoparticles encapsulated by carbon (Cu-NPs@C) were synthesized by a two-step method by mixing cupric chloride and glucose in a solution, followed by carbonization. The microstructures and antibacterial activities of the Cu-NPs@C samples were characterized by TEM, XRD, XPS, nitrogen adsorption and antibacterial activity tests. Results indicated that the as-synthesized Cu-NPs had a FCC crystal structure and a spherical morphology of diameter 4-46 nm and were well dispersed in the porous graphitic carbon layers. When the mass ratio of cupric chloride to glucose was less than 1:5, the Cu-NPs@C were of pure metallic copper without any oxides, and were stable against ambient air oxidation. The Cu-NPs@C synthesized with a mass ratio of cupric chloride to glucose of 1:5 had a specific surface area of 418 m²/g, which showed much higher antibacterial activities against three different common bacteria (Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa) than pure nano-copper powder. It was believed that the carbon layers are responsible for capturing the bacteria while the copper ions released from the copper nanoparticles kill them. The outer carbon layers effectively protected the metallic copper inside from oxidation. These findings indicate that Cu-NPs@C can be used as a stable antibacterial agent in biomedical applications.
- Carbon materials,
- Copper nanoparticle,
- Facile synthesis,
- Antimicrobial properties

FullText(HTML)

References(39)

References

Ran X G, Wang L Y, Cao D R, et al. Synthesis characterization and in vitro biological activity of cobalt(Ⅱ), copper(Ⅱ) and zinc(Ⅱ) schiff base complexes derived from salicylaldehyde and D, L-selenomethionine[J]. Appl Organomet Chem, 2011, 25:9-15.

Ananth A, Dharaneedharan S, He M S, et al. Copper oxide nanomaterials:Synthesis, characterization and structure-specific antibacterial performance[J]. Chem Eng, 2015, 262:179-188.

Kalaivani S, Kishore S R, Ganesan V, et al. Effect of copper (Cu²⁺) inclusion on the bioactivity and antibacterial behavior of calcium silicate coatings on titanium metal[J]. J Mater Chem B,2014, 2:846-858.

Mohammad H, Ashkan B, Ehsan S, et al. Electrophoretic-deposited hydroxyapatite-copper nanocomposite as an antibacterial coating for biomedical applications[J]. Surface and Coatings Technology, 2017, 321:171-179.

Hegab H M, ElMekawy A, Zou L, et al. The controversial antibacterial activity of graphene-based materials[J]. Carbon, 2016, 105:362-376.

Tang C L, Hu D M, Cao Q Q, et al. Silver nanoparticles-loaded activated carbon fibers using chitosan as binding agent:Preparation, mechanism, and their antibacterial activity[J]. Applied Surface Science, 2017, 394:457-465.

Nicoletta D V, Amalia C, Anna L I, et al. Aerosol-assisted low pressure plasma deposition of antimicrobial hybrid organic-inorganic Cu-composite thin films for food packaging applications[J]. Innovative Food Science and Emerging Technologies, 2015, 41:130-134.

Wahid F, Wang H S, Lu Y S, et al. Preparation, characterization and antibacterial applications ofcarboxymethyl chitosan/CuO nanocomposite hydrogels[J]. International Journal of Biological Macromolecules, 2017, 101, 690-695.

Gao F, Pang H, Xu S P, et al. Copper-based nanostructures:Promising antibacterial agents and photocatalysts[J]. Chem Commun, 2009, 3571-3573.

Yang J G, Zhou Y L, Okamoto T, et al. Preparation of oleic acid-capped copper nanoparticles[J]. Chemistry Letters, 2006, 35:1190-1192.

Markovi?a Z M, Matijaševi?d D M, Pavlovic V B, et al. Antibacterial potential of electrochemically exfoliated graphene sheets[J]. Journal of Colloid and Interface Science, 2017, 500:30-43.

Xiong L, Tong Z H, Chen J J, et al. Morphology-dependent antimicrobial activity of Cu/Cu_<i>xO nanoparticles[J]. Ecotoxicology, 2015, 24:2067-2072.

Kim Y H, Lee D K, Cha H G, et al. Preparation and characterization of the antibacterial Cu nanoparticle formed on the surface of SiO₂ nanoparticles[J]. J Phys Chem B, 2006, 110:24923-24928.

Dement'eva O V, Rudoy V M. Copper nanoparticles synthesized by the polyol method and their oxidation in polar dispersion media:The influence of chloride and acetate ions[J]. Colloid J, 2012, 74:668-674.

Liu Y Y, Liu D M, Chen S Y, et al. In situ synthesis of hybrid nanocomposite with highly order arranged amorphous metallic copper nanoparticle in poly(2-hydroxyethyl methacrylate) and its potential for blood-contact uses[J]. Acta Biomater, 2008, 4:2052-2058.

Deng D, Cheng Y, Jin Y, et al. Antioxidative effect of lactic acid-stabilized copper nanoparticles prepared in aqueous solution[J]. J Mater Chem, 2012, 22:23989-23995.

Baruah D, Konwar D. Cellulose supported copper nanoparticles as a versatile and efficient catalyst for the protodecarboxylation and oxidativedecarboxylation of aromatic acids under microwave heating[J]. Catalysis Communications, 2015, 69:68-71.

Javier S C, Heriberto E G, Gabriel A N, et al. A green synthesis of copper nanoparticles using native cyclodextrins as stabilizing agents[J]. Journal of Saudi Chemical Society, 2017, 21:341-348.

Chandra S, Kumar A, Tomar P K, et al. Synthesis and characterization of copper nanoparticles by reducing agent[J]. J Saudi Chem Soc, 2014, 18:149-153.

Khanna P K, Gaikwad S, Adhyapak P V, et al. Synthesis and characterization of copper nanoparticles[J]. Mater Lett, 2007, 61:4711-4714.

Usman M S, Ibrahim N A, Shameli K, et al. Copper nanoparticles mediated by chitosan:Synthesis and characterization via chemical method[J]. Molecules, 2012, 17:14928-14936.

Ayesha K, Rashid A, Younas R A, et al. Chemical reduction approach to the synthesis of copper nanoparticles[J]. Int Nano Lett, 2016, 6:21-26.

Candy N C, Behnke J L, Strickland A D, et al. Copper based nanostrucured coatings on natural cellulose:Nanocomposites exhibiting rapid and efficient inhibition of a multi-drug resistant wound pathogen baumanni A and Mammolian cell biocompatibility in vitro[J]. Advanced Functional Materials, 2011, 21:2506-2514.

Samavati A, Ismail A F. Antibacterial properties of copper-substituted cobalt ferritenanoparticles synthesized by co-precipitation method Alireza[J]. Particuology, 2017, 30:158-163.

Li M, Xiang K, Luo G, et al. Preparation of monodispersed copper nanoparticles by an environmentally friendly chemical reduction[J]. Chin J Chem, 2013, 31:1285-1289.

An Y Z, Wang C H, Miao P, et al. Improved decontamination performance of biofilm systems using carbon fibers as carriers for microorganisms[J]. New Carbon Materials, 2018, 33(2):188-192.

Ramyadevi J, Jeyasubramanian K, Marikani A, et al. Synthesis and antibacterial activity of copper nanoparticles[J]. Materials Letters, 2014, 71:114-116.

Krystof D, Pavel U, Marie S, et al. Copper nanoparticles in glycerol-polyvinyl alcohol matrix:In situ preparation, stabilisation and antimicrobial activity[J]. Journal of Alloys and Compounds, 2017, 697:147-155.

Li Y F, Liu Y Z, Liang Y, et al. Preparation of nitrogen-doped graphene/activated carboncomposite papers to enhance energy storage in supercapacitors[J]. Appl. Phys. A, 2017, 123:566.

Lemire J A, Harrison J J, Turner R J, et al. Antimicrobial activity of metals:Mechanisms, molecular targets and applications[J]. Nat Rev Microbiol, 2013, 11:371-384.

Li Y Y, Li B J, Wu Y H, et al. Preparation of carboxymethyl chitosan/copper composites and their antibacterial properties[J]. Materials Research Bulletin, 2013, 48:3411-3415.

Xiong J, Wang Y, Xue Q, et al. Synthesis of highly stable dispersions of nanosized copper particles using L-ascirbic acid[J]. Green Chem, 2011, 13:900-904.

Niasari M S, Davar F, Mir N, et al. Synthesis and characterization of metallic copper nanoparticles via thermal decomposition[J]. Polyhedron, 2008, 27:3514-3518.

Rehana D, Mahendiran D, Senthil K R, et al. Evaluation of antioxidant and anticancer activity of copper oxide nanoparticles synthesized using medicinally important plant extracts[J]. Biomedicine and Pharmacotherapy, 2017, 89:1067-1077.

Chen H F, Cao Y, Wei E Z, et al. Facile synthesis of graphene nano zero-valent iron composites and their efficient removal of trichloronitromethane from drinking water[J]. Chemosphere, 2016, 146:32-39.

Zhang B B, Song J L, Yang G Y, et al. Large-scale production of high-quality graphene using glucose and ferric chloride[J]. Chem Sci, 2014, 5:4656-4660.

孙鹏,隋铭皓,盛力,等. 载铜多壁碳纳米管的抗菌活性研究[J]. 功能材料, 2015,46(2):02089-02094. (Sun P, Sui M H, Sheng L, et al. Antibacterial activity of copper nanoparticles supported on multi-walled carbon nanotube[J]. Journal of Functional Materials, 2015, 46(2):02089-02094.)

Akasaka T, Watari F. Capture of bacteria by flexible carbon nanotubes[J]. Acta Biomaterialia, 2009, 5(2):607-612.

He M, Lu L Y, Zhang J C, et al. Facile preparation of L-ascorbic acid-stabilized copper-chitosan nanocomposites with high stability and antimicrobial properties[J]. Sci Bull, 2015, 60:227-234.

Relative Articles

Supplements(0)

Cited By

Proportional views