活性炭对扑热息痛的吸附行为和体外释放性能

The adsorption by and release of paracetamol from activated carbon (AC) with different pore structures and surface chemical properties were studied. The pore structure, specific surface area, surface chemical properties and pH at the point of zero charge of the AC were tested with N2 adsorption, Boehm titration and mass titration respectively. An AC with high specific surface area, and abundant mesopores ranging between 2 and 11 nm, exhibited excellent adsorption performance to paracetamol. Its adsorption capacity was 358mg/g, and its total release rate was 7% in 12h. The adsorption capacity of an AC with wider pore size distribution was 281mg/g and its total release rate reached 27% in 12h. The paracetamol adsorption capacity was higher on the AC which had a higher content of surface oxygen groups and exhibited an acidic character.