YU Shi-ping1, 2. The distribution of intravenously administered functionalized carbon nanotubes in rabbit tissue and their urinary excretion. New Carbon Mater., 2012, 27(6): 421-426.
Citation:
YU Shi-ping1, 2. The distribution of intravenously administered functionalized carbon nanotubes in rabbit tissue and their urinary excretion. New Carbon Mater., 2012, 27(6): 421-426.
YU Shi-ping1, 2. The distribution of intravenously administered functionalized carbon nanotubes in rabbit tissue and their urinary excretion. New Carbon Mater., 2012, 27(6): 421-426.
Citation:
YU Shi-ping1, 2. The distribution of intravenously administered functionalized carbon nanotubes in rabbit tissue and their urinary excretion. New Carbon Mater., 2012, 27(6): 421-426.
College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, China|2.Second Hospital of Shanxi Medical University, Taiyuan 030001| China|3.General Hospital of Yangquan Coal Industry Group Co.,Ltd,Yangquan 045000| China|4.Shanxi Academy of medical Sciences,Shanxi Da Yi Hospital, Taiyuan 030032| China
Funds:
Project supported by the Natural Science Foundation for Young Scientists of Shanxi Province, China(2008021047).
Diethylenetriaminepentaacetic acid-functionalized multi-wall carbon nanotubes (MWCNT-DTPA) were labeled by 99mTc and intravenously administered to rabbits, the radioactivity in different organs was scanned by single photon emission computed tomography and a well-type γ counter. Results showed that the administered MWCNT-DTPA-99mTc was mainly distributed in heart, liver, spleen and kidney. Centrifugate from urine was subjected to transmission electron microscopy analysis which showed that MWCNTs could be excreted through the urinary system.
DownLoad: