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Research progress on the biomedical uses of graphene and its derivatives

LIU Yang DING Jing WANG Qi-qi WEN Mei-ling TANG Ting-ting LIU Yong YUAN Rong LI Yong-feng AN Mei-wen

刘阳, 丁婧, 王奇奇, 文美玲, 唐婷婷, 刘勇, 袁蓉, 李永锋, 安美文. 石墨烯及其衍生物在生物医药方面的研究进展. 新型炭材料, 2021, 36(4): 779-793. doi: 10.1016/S1872-5805(21)60073-2
引用本文: 刘阳, 丁婧, 王奇奇, 文美玲, 唐婷婷, 刘勇, 袁蓉, 李永锋, 安美文. 石墨烯及其衍生物在生物医药方面的研究进展. 新型炭材料, 2021, 36(4): 779-793. doi: 10.1016/S1872-5805(21)60073-2
LIU Yang, DING Jing, WANG Qi-qi, WEN Mei-ling, TANG Ting-ting, LIU Yong, YUAN Rong, LI Yong-feng, AN Mei-wen. Research progress on the biomedical uses of graphene and its derivatives. New Carbon Mater., 2021, 36(4): 779-793. doi: 10.1016/S1872-5805(21)60073-2
Citation: LIU Yang, DING Jing, WANG Qi-qi, WEN Mei-ling, TANG Ting-ting, LIU Yong, YUAN Rong, LI Yong-feng, AN Mei-wen. Research progress on the biomedical uses of graphene and its derivatives. New Carbon Mater., 2021, 36(4): 779-793. doi: 10.1016/S1872-5805(21)60073-2

石墨烯及其衍生物在生物医药方面的研究进展

doi: 10.1016/S1872-5805(21)60073-2
基金项目: 国家自然科学基金项目(31870934);国家自然科学青年项目(12002232);山西省白求恩医院院基金(2019YJ12)
详细信息
    通讯作者:

    李永锋,副教授. E-mail:liyongfeng@tyut.edu.cn

    安美文,教授. E-mail:meiwen_an@163.com

  • 中图分类号: R751

Research progress on the biomedical uses of graphene and its derivatives

Funds: This work was supported by National Natural Science Foundation of China (31870934), National Natural Science Foundation of China Youth Project (12002232), College fund of Shanxi Bethune Hospital (2019YJ12)
More Information
  • 摘要: 石墨烯是紧密堆积在二维蜂窝状晶格中一层扁平的碳原子单层,具有良好的光学性、导电性、力学性、低毒性、抗菌性、生物相容性和稳定性。氧化石墨烯、还原氧化石墨烯是石墨烯的衍生物,具备石墨烯类似的性质,石墨烯及其衍生物的研究进展十分迅速,在生物医药方向拥有较大的应用潜力。本文从石墨烯及其衍生物的毒性、抗菌性的角度出发,综述了石墨烯及其衍生物在治疗皮肤创伤、治疗肿瘤、促进骨骼肌和骨再生、载药、诊断疾病等方面的应用,并提出了目前所存在的问题和解决对策,展望了未来石墨烯基材料的研究发展前景。
  • FIG. 783.  FIG. 783.

    FIG. 783.. 

    Figure  1.  Schematic diagram of the GO−PEG−PEI-based Cas9/sgRNA delivery system ( Reprinted with permission)[11].

    Figure  2.  Schematic illustrations for the preparation of 2D TRB-ZnO@Gr nanosheets (Reprinted with permission)[20].

    Figure  3.  Diagrammatic sketch of HA-DA/rGO hydrogel preparation: (a) preparation scheme of HA-DA polymer, (b) rGO@PDA and (c) scheme of HA-DA/rGO hydrogel and the original, bending, compressing, self-healing representation and the application in wound healing. Scale bar: 5 mm. (DA and PDA are abbreviated forms of dopamine and polydopamine, respectively) (Reprinted with permission)[50].

    Figure  4.  Schematic diagram describing different roles of graphene in cancer theranostics (Reprinted with permission)[93].

    Figure  5.  Multi-functional graphene composites.

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出版历程
  • 收稿日期:  2021-05-11
  • 修回日期:  2021-06-27
  • 网络出版日期:  2021-07-05
  • 刊出日期:  2021-07-30

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