Abstract: Graphene was synthesized by the detonation-assisted reduction of graphite oxide (GO) prepared by the modified Hummers method. Nitrogen-doped reduced GO（N-RGO）was obtained through an in-situ nitrogen-doping during detonation. The morphology, elemental composition and structure of the N-RGO were characterized by TEM, SEM, IR, XPS, XRD and Raman spectroscopy. The catalytic activity of the N-RGO as a fuel cell electrode for the oxygen reduction reaction (ORR) was investigated by a rotating ring disk electrode technique. Results showed that the GO was exfoliated and reduced to few layer graphene by the detonation. The oxygen-containing species of GO were reduced and the C/O molar ratio was increased to 26.2, which is much higher than for RGO. Nitrogen, as high as 2.11 at%, was incorporated into the graphene structure. The diffusion-limited current for ORR increased from 0.24 mA for RGO to 0.49 mA for N-RGO, indicating a higher catalytic activity of N-RGO for ORR than that of RGO.